101 - Document - Document and Entity Information link:calculationLink link:presentationLink link:definitionLink 103 - Statement - Balance Sheets link:calculationLink link:presentationLink link:definitionLink 104 - Statement - Balance Sheets (Parenthetical) link:calculationLink link:presentationLink link:definitionLink 105 - Statement - Statements of Operations link:calculationLink link:presentationLink link:definitionLink 106 - Statement - Statements of Convertible Preferred Stock and Stockholders' Deficit link:calculationLink link:presentationLink link:definitionLink 107 - Statement - Statements of Convertible Preferred Stock and Stockholders' Deficit (Parenthetical) link:calculationLink link:presentationLink link:definitionLink 108 - Statement - Statements of Cash Flows link:calculationLink link:presentationLink link:definitionLink 109 - Disclosure - Description of Business link:calculationLink link:presentationLink link:definitionLink 110 - Disclosure - Summary of Significant Accounting Policies link:calculationLink link:presentationLink link:definitionLink 111 - Disclosure - Fair Value of Financial Instruments link:calculationLink link:presentationLink link:definitionLink 112 - Disclosure - Property and Equipment, Net link:calculationLink link:presentationLink link:definitionLink 113 - Disclosure - Related Party Convertible Promissory Notes link:calculationLink link:presentationLink link:definitionLink 114 - Disclosure - Convertible Preferred Stock Warrants link:calculationLink link:presentationLink link:definitionLink 115 - Disclosure - Series A Warrants and Series B Warrants link:calculationLink link:presentationLink link:definitionLink 116 - Disclosure - Line of Credit link:calculationLink link:presentationLink link:definitionLink 117 - Disclosure - Commitments link:calculationLink link:presentationLink link:definitionLink 118 - Disclosure - Capital Stock link:calculationLink link:presentationLink link:definitionLink 119 - Disclosure - Stock Option Compensation link:calculationLink link:presentationLink link:definitionLink 120 - Disclosure - GSK License Agreement link:calculationLink link:presentationLink link:definitionLink 121 - Disclosure - Income Taxes link:calculationLink link:presentationLink link:definitionLink 122 - Disclosure - Defined Contribution Plan link:calculationLink link:presentationLink link:definitionLink 123 - Disclosure - Subsequent Events link:calculationLink link:presentationLink link:definitionLink 124 - Disclosure - Summary of Significant Accounting Policies (Policies) link:calculationLink link:presentationLink link:definitionLink 125 - Disclosure - Description of Business (Tables) link:calculationLink link:presentationLink link:definitionLink 126 - Disclosure - Summary of Significant Accounting Policies (Tables) link:calculationLink link:presentationLink link:definitionLink 127 - Disclosure - Fair Value of Financial Instruments (Tables) link:calculationLink link:presentationLink link:definitionLink 128 - Disclosure - Property and Equipment, Net (Tables) link:calculationLink link:presentationLink link:definitionLink 129 - Disclosure - Convertible Preferred Stock Warrants (Tables) link:calculationLink link:presentationLink link:definitionLink 130 - Disclosure - Series A Warrants and Series B Warrants (Tables) link:calculationLink link:presentationLink link:definitionLink 131 - Disclosure - Capital Stock (Tables) link:calculationLink link:presentationLink link:definitionLink 132 - Disclosure - Stock Option Compensation (Tables) link:calculationLink link:presentationLink link:definitionLink 133 - Disclosure - Income Taxes (Tables) link:calculationLink link:presentationLink link:definitionLink 134 - Disclosure - Description of Business - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 135 - Disclosure - Description of Business - Summary of Initial Public Offering (Detail) link:calculationLink link:presentationLink link:definitionLink 136 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 137 - Disclosure - Summary of Significant Accounting Policies - Schedule of Calculation of Basic Earnings per Share and Diluted Earnings per Share (Detail) link:calculationLink link:presentationLink link:definitionLink 138 - Disclosure - Summary of Significant Accounting Policies - Schedule of Potentially Dilutive Securities Outstanding Excluded from Computations of Diluted Weighted-Average Shares Outstanding (Detail) link:calculationLink link:presentationLink link:definitionLink 139 - Disclosure - Fair Value of Financial Instruments - Summary of Financial Instruments Measured at Fair Value on Recurring Basis (Detail) link:calculationLink link:presentationLink link:definitionLink 140 - Disclosure - Property and Equipment, Net - Schedule of Property and Equipment (Detail) link:calculationLink link:presentationLink link:definitionLink 141 - Disclosure - Property and Equipment, Net - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 142 - Disclosure - Related Party Convertible Promissory Notes - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 143 - Disclosure - Convertible Preferred Stock Warrants - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 144 - Disclosure - Convertible Preferred Stock Warrants - Fair Value of Convertible Preferred Stock Warrant Liability (Detail) link:calculationLink link:presentationLink link:definitionLink 145 - Disclosure - Convertible Preferred Stock Warrants - Summary of Outstanding Convertible Preferred Stock Warrants (Detail) link:calculationLink link:presentationLink link:definitionLink 146 - Disclosure - Series A Warrants and Series B Warrants - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 147 - Disclosure - Series A Warrants and Series B Warrants - Fair Value of Convertible Preferred Stock Warrant Liability (Detail) link:calculationLink link:presentationLink link:definitionLink 148 - Disclosure - Series A Warrants and Series B Warrants - Summary of Outstanding Series B Warrants and Fair Market Values (Detail) link:calculationLink link:presentationLink link:definitionLink 149 - Disclosure - Line of Credit - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 150 - Disclosure - Commitments - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 151 - Disclosure - Capital Stock - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 152 - Disclosure - Capital Stock - Summary of Common Stock Issued and Outstanding (Detail) link:calculationLink link:presentationLink link:definitionLink 153 - Disclosure - Capital Stock - Summary of Convertible Preferred Stock (Detail) link:calculationLink link:presentationLink link:definitionLink 154 - Disclosure - Stock Option Compensation - Stock Option Plan - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 155 - Disclosure - Stock Option Compensation - Summary of Stock Based Compensation Expense (Detail) link:calculationLink link:presentationLink link:definitionLink 156 - Disclosure - Stock Option Compensation - Schedule of Fair Value of Award Granted Using Black-Scholes Option Pricing Model (Detail) link:calculationLink link:presentationLink link:definitionLink 157 - Disclosure - Stock Option Compensation - Summary of Stock Option Transactions (Detail) link:calculationLink link:presentationLink link:definitionLink 158 - Disclosure - GSK License Agreement - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 159 - Disclosure - Income Taxes - Reconciliation of Income Tax Expense by Applying Statutory U.S. Federal Income Tax Rate to Income Before Income Taxes (Detail) link:calculationLink link:presentationLink link:definitionLink 160 - Disclosure - Income Taxes - Reconciliation of Income Tax Expense by Applying Statutory U.S. Federal Income Tax Rate to Income Before Income Taxes (Parenthetical) (Detail) link:calculationLink link:presentationLink link:definitionLink 161 - Disclosure - Income Taxes - Significant Components of Company's Deferred Tax Assets and Liabilities (Detail) link:calculationLink link:presentationLink link:definitionLink 162 - Disclosure - Income Taxes - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 163 - Disclosure - Income Taxes - Summary of Gross Unrecognized Tax Benefits (Detail) link:calculationLink link:presentationLink link:definitionLink 164 - Disclosure - Defined Contribution Plan - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 165 - Disclosure - Subsequent Events - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink